All One Health Content
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Gut microbes may help in recognizing and treating pancreatic cancer
A new international cooperation study indicates that in the future pancreatic cancer may be detected at an early stage with the help of gut microbes. Gut microbes may also offer solutions for therapy development.
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Study highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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Broad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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Researchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.
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Evolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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Oxymatrine, a quinoline alkaloid derived from Sophora flavescens, inhibits the Malassezia biofilm
Oxymatrine not only controls Malassezia overgrowth but also manages psoriasis symptoms, offering a dual-action mechanism for safer and more effective therapy, a new study shows.
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Scientists develop a treatment platform to disable the ‘biofilm’ shield of superbugs
Researchers have developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down MRSA biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.
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Researchers identify new llama-derived antibodies against current and future coronaviruses
Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants.
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Fusobacterium nucleatum in colorectal cancer: Ally mechanism and targeted therapy strategies
A recent review systematically outlines the pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and summarizes both current and emerging strategies for its therapeutic targeting.
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GeneXpert MTB/RIF technology can distinguish non-tuberculous mycobacterial infection
Xpert Mycobacterium tuberculosis/rifampicin (Xpert MTB/RIF) in alveolar lavage fluid can not only detect rifampicin resistance but also distinguish pulmonary tuberculosis (TB) from non-tuberculosis mycobacterial (NTM) pulmonary disease.
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Epidemiological trends and serological profiles of respiratory pathogens in Guangzhou
A new study analyzing the epidemiological trends of multiple respiratory pathogens in Guangzhou, China, from 2013 to 2023, indicates the need for age- and gender-specific approaches to infection prevention and management.
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Probiotic breakthrough: Bifidobacterium animalis subsp. Lactis A6 shows promise in alleviating comorbid constipation and depression
A new study clarifies how gut microbes influence mental health and offers a safe, targeted probiotic therapy, Bifidobacterium animalis subsp. Lactis A6 (BBA6), for comorbid constipation and depression.
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Can a psychedelic compound from mushrooms benefit people with cancer and major depression?
New results from a clinical trial reveal that a single dose of psilocybin—a naturally occurring psychedelic compound found in mushrooms—can provide sustained reductions in depression and anxiety in individuals with cancer suffering from major depressive disorder.
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Vaccinated patients hospitalized with COVID-linked acute kidney injury less likely to need dialysis after discharge
Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests. The study found vaccinated patients were less likely to stay on dialysis after discharge, and more likely to survive, than unvaccinated patients.
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Ribosome profiling identifies thousands of new viral protein-coding sequences
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), scientists have identified more than 4000 open reading frames (ORFs) across 679 human-associated viral genomes.
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When bacteria get hungry, they kill – and eat – their neighbors
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors. The researchers show that under nutrient-limited conditions, bacteria use a specialized weapon — the Type VI Secretion System (T6SS) — to attack, kill, and slowly absorb nutrients from other bacterial cells.
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An oral cholera vaccination campaign aims to reach more than 2.6 million people in Sudan’s Khartoum State
A 10-day reactive oral cholera vaccination campaign, launched on 10 June in 5 localities in Sudan’s Khartoum State, aims to protect more than 2.6 million people aged 1 year and above from cholera infection, interrupt transmission and help contain the cholera outbreak.
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2 million Americans with hepatitis C at risk if Supreme Court cancels free preventative care, study finds
A ruling overturning the Affordable Care Act (ACA) coverage mandate has the potential to dramatically change the landscape for early detection and treatment of hepatitis C virus in the U.S., according to a new paper.
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A combination of exercise and omega-3 reduces the severity of tooth root infections
Rats that exercised and took fatty acid supplements responded better to bacteria and the inflammatory process of apical periodontitis, which can occur when caries reach the root canal and cause an infection.
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Is your gut microbiome a calorie ‘super harvester’?
A little-known microbe makes methane in your gut — and may help you get more calories from food, according to a new study. Researchers found that people whose gut microbiomes produce a lot of methane are especially good at unlocking extra energy from a high-fiber diet.